产品货号：
Z17199
中文名称：
GPX4抗体
英文名称：
Anti-GPX4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GPX4 Antibody |
| 指标别名 | GPX4;Phospholipid hydroperoxide glutathione peroxidase;PHGPx;EC 1.11.1.12;Glutathione peroxidase 4;GPx-4;GSHPx-4 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | IHC |
| 基因名称 | GPX4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human GPX4(30-60aa ASRDDWRCARSMHEFSAKDIDGHMVNLDKYR),different from the related mouse sequence by one amino acid,and from the related rat sequence by two amino acids. |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Glutathione peroxidase 4,also known as GPX4,is an enzyme that in humans is encoded by the GPX4 gene.This gene encodes a member of the glutathione peroxidase protein family.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide,organic hydroperoxide,and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage.Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine.The encoded protein has been identified as a moonlighting protein based on its ability to serve dual functions as a peroxidase as well as a structural protein in mature spermatozoa.Through alternative splicing and transcription initiation,rat produces proteins that localize to the nucleus,mitochondrion,and cytoplasm.In humans,alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | P36969 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | glutathione peroxidase 4 |
| 蛋白名全称 | Phospholipid hydroperoxide glutathione peroxidase,mitochondrial |
| 推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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